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Maddi Hebebrand is an associate editor of 

and joined the MJH Life Sciences team in May 2024. She attended Baldwin Wallace University, studying Media Production and Film, and received her Masters in Digital Media from Ohio University. When she's not writing, Maddi loves to read, attend concerts and spend time with her family. 

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Explore the top headlines of the week including insights on recalls, expert pearls, and more. 

Journal Digest: April 30

Catch up on dermatology news, highlights, and insights from the past 24 hours.

Daily Derm Times: April 29, 2025

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Acting upstream of cytokines may hold the key to improving biologic efficacy and itch relief in AD.

Understanding the Role of OX40 in Next-Generation Eczema Therapies

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Authors

Graham T. Illing, PhD, is a CMC director and group manager of global regulatory affairs at AstraZeneca (Macclesfield, England).

Final Thoughts: The Importance of Comparative Studies in AD

Panelists offer concluding insights and emphasize the critical role of comparative studies in advancing atopic dermatitis treatment strategies.

clinical

Video Series

Hyperhidrosis is not rare. According to the 

, approximately 385 million people worldwide live with hyperhidrosis.

In fact, they note that the amount of people living with chronic, excessive sweating is even higher than the amount of people living with other dermatologic conditions like psoriasis.

Just how common is hyperhidrosis in real-world comparisons?

The prevalence of hyperhidrosis is much higher in younger populations than in the general population, with 8.8% of individuals between the ages of 18 to 39 years old living with the condition. 

When comparing these statistics to everyday, common occurrences like hair color, the number of people with hyperhidrosis is greater than the 1% of individuals with natural red hair and 2% of individuals with natural blond hair. 

Despite how common hyperhidrosis is, it is estimated that 27% of those with the condition never receive a diagnosis.

 wants to hear from you. What percentage of the global population is estimated to have hyperhidrosis?

 to share your hyperhidrosis insights or research.

Albert. Fact check: Hyperhidrosis - International Hyperhidrosis Society: Official site. Home - International Hyperhidrosis Society. October 24, 1970. Accessed November 16, 2023. 

https://www.sweathelp.org/home/news-blog/542-fact-check-hyperhidrosis.html

Hyperhidrosis affects approximately 385 million people globally, surpassing the prevalence of other dermatologic conditions like psoriasis. It is notably more common in younger populations, with 8.8% of individuals aged 18 to 39 experiencing the condition. Comparatively, hyperhidrosis is more prevalent than natural red or blond hair, which affects 1% and 2% of the population, respectively. Despite its prevalence, 27% of those with hyperhidrosis remain undiagnosed. The article encourages engagement during Hyperhidrosis Awareness Month to share insights and research on the condition.

Click here to answer this week's poll for Hyperhidrosis Awareness Month.

Polls 

POLL: What Percent of the Global Population is Estimated to Have Hyperhidrosis?

 has asked our readers to share with us what conferences and meetings they are looking forward to or planning to attend in 2025.

Using these responses, we have compiled a list of dermatological meetings taking place this year.

Interested in sharing what conferences you are interested in or planning to attend this year? 

2025

The compilation of dermatological meetings for 2025 is based on reader responses about anticipated conferences. Dermatology professionals have shared their plans and interests regarding upcoming events. This list serves as a resource for those in the field to identify key gatherings in the dermatology community. Readers are encouraged to contribute their own conference interests by contacting the editorial team. This engagement helps to ensure a comprehensive overview of significant dermatological meetings, fostering a collaborative and informed professional community.

Dermatology Times asked our readers to share what conferences they are looking forward to in 2025.

Dermatology Conferences and Meetings Calendar: 2025

“Chronic hand eczema can be a tricky diagnosis and a tricky thing to treat, in part because we don't always agree on what the diagnosis is. As long as you've had multiple bouts of eczema on your hands in one year, or a particular symptom of patterns that have been going on for at least 3 months, you really fit the bill for chronic hand eczema,” said Raj Chovatiya, MD, PhD, MSCI, in an interview with 

Chovatiya, a board-certified dermatologist and clinical associate professor at Rosalind Franklin University Chicago Medical School, founder and director of the Center for Medical Dermatology and Immunology Research in Chicago, and a 

 Editorial Advisory Board member, recently discussed his approach to diagnosing and treating chronic hand eczema (CHE).

Raj Chovatiya, MD, PhD, MSCI, discusses his approach to diagnosing and treating chronic hand eczema.  

Addressing Diagnostic Ambiguity and Expanding Therapeutic Options in CHE 

CHE is a heterogeneous skin condition characterized mainly by 3 main etiologies: irritant contact dermatitis, allergic contact dermatitis, and atopic hand eczema. Each etiology has its own unique immune signature, and the condition can be overall difficult to treat, particularly in moderate to severe cases.

As Chovatiya noted, CHE can be difficult to diagnose due to the 3 etiologies not always predicting the way the condition will present on the hands. Generally, CHE can be defined by recurrent episodes of hand eczema over the span of a year or a persistent pattern lasting at least 3 months, according to Chovatiya.

He also noted that clinicians frequently face uncertainty about whether to treat CHE as contact dermatitis, atopic dermatitis, or a combination, and how extensively to pursue diagnostics. Chovatiya’s approach recommends starting with foundational strategies: barrier care with emollients, trigger avoidance, and limiting wet-to-dry exposure.

For initial pharmacologic treatment, topical corticosteroids or calcineurin inhibitors are appropriate. If patients show insufficient response after a few weeks of consistent use, escalation should be considered. Chovatiya anticipates delgocitinib, a topical pan-JAK inhibitor, will be a valuable next-line therapeutic given its ability to target multiple inflammatory pathways involved in CHE.

Regarding diagnostics, Chovatiya supports a selective approach to patch testing, particularly for patients with occupational exposures, refractory disease, or unclear clinical patterns. However, he cautioned against withholding treatment while awaiting diagnostic results.

In refractory cases, advanced therapies such as systemic immunosuppressants, phototherapy, or oral retinoids (e.g., alitretinoin, outside the US) may be warranted. While clinicians often turn to atopic dermatitis treatments such as biologics and oral JAK inhibitors, their efficacy in CHE is variable, demonstrating the need for therapies specifically approved for CHE.

To learn more about CHE and atopic dermatitis from Dr Chovatiya, 

register to attend Revolutionizing Atopic Dermatitis (RAD)

 in Nashville, Tennessee, June 6-7. Use code DT40 for 40% off your RAD 2025 registration.

Dubin C, Del Duca E, Guttman-Yassky E. Drugs for the treatment of chronic hand eczema: successes and key challenges. 

. 2020 Dec 31;16:1319-1332. doi: 10.2147/TCRM.S292504

Raj Chovatiya, MD, PhD, MSCI, discusses his approach to diagnosing and treating chronic hand eczema. 

Addressing Diagnostic Ambiguity and Expanding Therapeutic Options in CHE

“RAD is one-stop shop for everything happening in education, clinical practice, and research for atopic dermatitis,” said Raj Chovatiya, MD, PhD, MSCI, in an interview with 

 Editorial Advisory Board member, recently discussed the upcoming Revolutionizing Atopic Dermatitis (RAD) meeting in Nashville, Tennesse, June 6-7. Chovatiya will present numerous sessions on biologics, topicals, IL-31 vs IL-13, and more.

One-Stop Shop: RAD Offers Comprehensive Insights Into AD Diagnosis, Treatment, and Research

In his interview, Chovatiya highlighted the benefits of RAD as a premier destination for education, research, and clinical insights in atopic dermatitis (AD).

“Even if atopic dermatitis specifically isn't your primary interest as far as research or education… You're going to hear all about not only the approved items that are in your therapeutic repertoire, but also the emerging items that are coming out there. They're going to change your therapy,” Chovatiya noted.

The meeting, he explained, offers in-depth coverage of current FDA-approved therapies as well as investigational agents set to expand the treatment paradigm. Beyond pharmacologic updates, RAD provides an opportunity to explore disease burden, comorbidities, and adjacent eczematous conditions such as chronic hand eczema—areas often underrepresented in traditional AD education.

Chovatiya discussed RAD's role not only as an educational forum but also as a multidisciplinary networking opportunity. “RAD is a great place to not only meet people… but also a chance to catch up on research. There’s going to be a lot of great abstracts, posters, and late breakers that can allow you to see what's happening on the cutting edge,” he said, pointing to the emerging data that enable clinicians to stay at the forefront of innovation.

Positioned as a one-stop resource, RAD aims to elevate clinical care, offering clinicians the tools to optimize outcomes across the AD spectrum.

JAK Inhibitors in AD; June 6 - 9:10 am ET

Topicals and Biologics - When and Why; June 6 - 2:00 pm ET

Medical Crossfire: IL-31 and IL-13; June 7 - 11:40 am ET

To attend Chovatiya’s sessions and hear from other experts in AD, 

register for Revolutionizing Atopic Dermatitis

Raj Chovatiya, MD, PhD, MSCI, reviews the benefits of Revolutionizing Atopic Dermatitis as a disease-specific conference.

“JAK inhibitors have really given us additional options for therapy in the last few years that we didn't have for our patients, particularly oral therapeutics, something that's been lacking in this disease space,” said Raj Chovatiya, MD, PhD, MSCI, in an interview with 

Chovatiya, a board-certified dermatologist and clinical associate professor at the Rosalind Franklin University Chicago Medical School, founder and director of the Center for Medical Dermatology and Immunology Research in Chicago, and a 

 Editorial Advisory Board member, discussed the clinical advantages of JAK inhibitors for atopic dermatitis (AD), emphasizing their efficacy, dosing flexibility, and role as a personalized treatment option for patients with inadequate response to prior therapies.

Raj Chovatiya, MD, PhD, MSCI, provides insights on the clinical advantages of JAK inhibitors for atopic dermatitis. 

JAK Inhibitors as Flexible, Fast-Acting Option for Refractory AD 

As Chovatiya noted in his interview, JAK inhibitors have significantly expanded the therapeutic options for AD, particularly in the realm of systemic oral treatments. Chovatiya highlighted their impact as a long-awaited option for patients who either require flexibility in treatment or have not responded adequately to conventional therapies. JAK inhibitors provide a unique combination of efficacy, rapid onset of action, and adjustable dosing regimens—traits that are particularly valuable in real-world clinical settings.

Current FDA-approved JAK inhibitors for AD include oral abrocitinib (Cibinqo; Pfizer) and upadacitinib (Rinvoq; AbbVie), and topical ruxolitinib (Opzelura; Incyte). 

Chovatiya discussed the importance of a patient-specific, case-by-case approach when considering JAK inhibitors. Ideal candidates may include both treatment-naive individuals and those who have failed prior therapies. The key, he noted, is a balanced, transparent discussion with patients about potential benefits versus risks. For many, JAK inhibitors offer the possibility of significant improvement in pruritus and lesion burden, and the ability to tailor dose intensity can help align therapeutic outcomes with individual disease severity and lifestyle factors.

A practical advantage in clinical use is the capacity for dose modulation—intensifying treatment during flares or tapering when disease control is achieved. However, clinicians must communicate the need for initial laboratory monitoring and counsel on the low but notable risks of adverse effects, such as infection or thromboembolic events. Despite the typically low potential for adverse effects, Chovatiya reiterated the overall favorable safety profile of JAK inhibitors when appropriately selected and monitored.

Ultimately, JAK inhibitors represent a valuable, modern addition to the clinician’s toolbox by offering both clinical flexibility and efficacy in managing complex AD, particularly for patients seeking rapid and meaningful symptom relief.

To hear more about JAK inhibitor selection from Chovatiya, 

register to attend the 2025 Revolutionizing Atopic Dermatitis (RAD) Annual Meeting

 in Nashville, Tennessee, held June 6-7. Use code DT40 for 40% off your registration.

Raj Chovatiya, MD, PhD, MSCI, provides insights on the clinical advantages of JAK inhibitors for atopic dermatitis.

Graham Illing

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