November 28th 2024
Data from Galderma's OLYMPIA 1 trial was recently published in JAMA Dermatology.
November 19th 2024
Patients treated with dupilumab saw substantial healing, with over 70% achieving >50% lesion improvement in 24 weeks.
November 13th 2024
A study showed NB-UVB phototherapy effectively reduced prurigo nodularis symptoms, with 80% of patients achieving full response.
November 6th 2024
These findings can help clinicians better treat the psychosocial factors associated with the disease.
A post hoc analysis of OLYMPIA 1 and 2 trial data found significant improvement in the first 14 days of treatment.
Journal Digest: October 28
This review of the latest dermatologic studies includes discussions on the relationship between atopic dermatitis and prurigo nodularis, the use of upadacitinib for treating PN, and more.
Available Therapeutics and Upcoming Advancements in Atopic Dermatitis and Prurigo Nodularis
Shawn Kwatra, MD, reviews key highlights of his sessions at Fall Clinical 2024 on the latest updates in itch conditions.
Study Quantifies, Characterizes Health Care Burden of Prurigo Nodularis in England
The study represents the first to evaluate health care resource utilization among individuals with PN in England.
Safe and Effective: Upadacitinib Shows Promise in PN Treatment
Significant reductions in itch scores and improved assessments of PN severity and quality of life were observed throughout the study.
Clinical Features and Cytokine Pathways in Prurigo Nodularis vs Atopic Dermatitis
Jason Hawkes, MD, MS, emphasized the importance of biologic treatments transforming the management of both prurigo nodularis and atopic dermatitis.
Late-Breaking Data: 40-Week Efficacy and Safety of Oral Povorcitinib for Prurigo Nodularis
Shawn Kwatra, MD, presented the Incyte data at EADV 2024.
Prurigo Nodularis News: The Year Thus Far
Catch up on the latest news on prurigo nodularis advancements in 2024.
Abrocitinib Shows Promise for Prurigo Nodularis
The JAK1 inhibitor provided significant relief for 2 patients with refractory PN.
Approximately 65% of Dermatologists in Japan Report Dissatisfaction With Treatment Options for Severe Prurigo Nodularis
Researchers conducted a web-based survey to gain insights into current clinical practice for PN in Japan.
Study Outlines Prurigo Nodularis and Psychiatric Comorbidities
The review found that patients with PN are approximately 1.3 times more susceptible to depression and 1.9 times more likely to experience anxiety.
FDA Approves Nemolizumab for the Treatment of Prurigo Nodularis
Galderma’s nemolizumab is the first approved monoclonal antibody specifically inhibiting the signaling of IL-31.
Baldo Scassellati Sforzolini, MD, PhD, MBA: Expanding Nemolizumab’s Access
Scassellati Sforzolini discusses the significance of Galderma’s nemolizumab receiving 4 additional filing acceptances for prurigo nodularis and atopic dermatitis.
Incyte and CMS Collaborate to Develop Povorcitinib in Numerous Chinese Regions
Povorcitinib is being evaluated for non-segmental vitiligo, hidradenitis suppurativa, prurigo nodularis, asthma, and chronic spontaneous urticaria.
Late-Breaking Data: Povorcitinib Significantly Improves Itch and Lesions in Prurigo Nodularis
Shawn Kwatra, MD, shares positive updates on phase 2 oral povorcitinib for prurigo nodularis at AAD 2024.
Late-Breaking Data: Long-Term Safety and Efficacy of Largest Prurigo Nodularis Study Ever Conducted
Shawn Kwatra, MD, presented late-breaking data at AAD 2024 on the largest prurigo nodularis and nemolizumab clinical trial, OLYMPIA.
FDA Accepts Galderma’s BLA for Nemolizumab for the Treatment of Prurigo Nodularis and Atopic Dermatitis
The FDA has also granted nemolizumab Priority Review for prurigo nodularis.
Cryosim-1 Safe, Effective in Patients With Prurigo Nodularis
A randomized, placebo-controlled trial of the selective transient receptor potential melastatin 8 agonist explored its efficacy and safety in PN.