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Dallas - Non-lentigo maligna melanoma in-situ and lentigo malignamelanoma in-situ are clinically distinct entities and also differ in themargins necessary for complete excision. For each type of lesion, however,the recommended 5-mm excision margin is often inadequate for cure, DavidKao, M.D., said at the annual meeting of the American Society for DermatologicSurgery and the American College of Mohs Micrographic Surgery and CutaneousOncology.