The Weekly Roundup: August 5-9

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Climate and Atopic Dermatitis: 5 Recent Studies to Consider

A growing body of research is dedicated to understanding how various climatic elements impact AD.

The Role of Vitamins and Nutrients in Rosacea Management

A recent study reviewed the current evidence on the impact of key vitamins and minerals on rosacea and provided clinical recommendations.

Topical vs Systemic Treatments: Rosacea Lesion Reduction Compared

A review of 43 studies found that systemic treatments generally provide greater reductions in rosacea ILs compared to topical therapies.

Journal Digest: August 5

This week’s collection of the latest dermatologic studies includes oral dutasteride for frontal fibrosing alopecia, effects of air pollutants for patients with acne, bimekizumab in patients with PsA without methotrexate, and itepekimab for adults with moderate to severe AD.

Hand Dermatitis Relief: Cotton Gloves vs Sympatex Liners

Participants experienced improvements with both glove types, though cotton gloves were generally preferred for comfort and Sympatex for tactile sensitivity.

Relationship Between Vitiligo and Psoriasis May Be Due, In Part, to Immunity

Skin with vitiligo and psoriasis shows increased immune cell type, with a Mendelian analysis finding no causal link between the conditions.

Microneedling and CO2 Lasers Enhance Acne Treatment

A recent study revealed that CO2 fractional laser was significantly more effective than microneedling for acne treatment with ALA-PDT.

Breakthrough CRISPR/Cas9 Technique Achieves 95% Exon Deletion for Epidermolysis Bullosa Treatment

A new method using 2 single-guide RNA/Cas9 tools to target 3 specific COL7A1 gene segments with harmful mutations successfully removed up to 95% of those segments.

Q&A: Alumis Inc. Initiates Phase 3 Clinical Program for ESK-001 in Plaque Psoriasis

Alumis' Martin Babler shared insights into the program for the TYK2 inhibitor and the company's next steps for its development.

Screening Questionnaire Developed for Type 2 Inflammation Diseases

The 15-piece questionnaire is designed to be quick and easy to use during consultations, with particular benefits across numerous specialties.

JAK Inhibition With Upadacitinib and Abrocitinib Shows Potential in Rosacea Treatment

Recent research evaluated 6 patients with rosacea treated with JAK1 inhibitors upadacitinib and abrocitinib.

Vitiligo Risk Alleles Vary Across Different Populations, According to Study

The findings highlight the need for diverse genetic studies to understand their broader impact on autoimmune diseases.

Experts Form Consensus on AI's Role in Aesthetics

A group of international experts focused on the technology’s potential to standardize and enhance patient assessments.

From OX40 Inhibition to Pediatric Pearls: Back-to-School Time for Physicians and Patients Alike

Our August issue covers common back-to-school skin conditions, psoriasis research, OX40 inhibition for atopic dermatitis, and pediatric dermatology meeting highlights.

Study Achieves International Consensus for Methotrexate Dosing in Patients With Atopic Dermatitis

Researchers said they hope this consensus guides prescribing decisions among clinicians and encourages development of a standard approach.

Extended Guselkumab Dosing Proven Effective for Psoriasis

Both 8-week and 16-week dosing intervals of guselkumab achieved similar clinical outcomes and patient-reported responses in the GUIDE trial.

Women With Skin of Color are Underrepresented in Studies of Treatments for Vulvar Lichen Sclerosus

Topical corticosteroids are the gold standard treatment for VLS, yet women with skin of color are not represented in studies.

Back to School, Back in the Spotlight

Young patients are heading back to school, and common skin issues like acne, eczema, warts, and pigmentation can affect their confidence, Shanna Miranti, MPAS, PA-C, writes.

FDA Approves Denileukin Diftitox for Adults With Relapsed or Refractory Cutaneous T-Cell Lymphoma

The approval is supported by positive phase 3 data for Lymphir in this indication.

Piperacillin/Tazobactam Shows Potential in Severe HS Treatment

Follow-up results showed that 6 out of 9 patients achieved HiSCR at 3 months, with 5 maintaining this response at 6 months.

Vitiligo Care Personalized for Each Patient: Part 1

Rocco Serrao, MD, FAAD, reviews a case study of a 20-year-old man with segmental vitiligo and the psychological impact of his vitiligo.

Diamond-Augmented Zinc Oxide Technology Demonstrates Efficacy in Wound Healing, Collagen Synthesis, and More

ND-ZnO technology also demonstrated substantial skin permeation and active ingredient delivery.

Psoriasis Does Not Increase Risk of COPD, According to New Study

Increased COPD prevalence in patients with psoriasis likely reflects smoking correlation, according to researchers.

Navigating the Challenges of Melasma Treatment and Achieving Trial Equity in Melanin-Rich Skin

Melasma, challenging due to varied pigmentation in different skin types, requires personalized, tailored care.

Study Identifies 3 Hidradenitis Suppurativa Clusters and Evaluates Secukinumab Efficacy

Secukinumab improved outcomes in all clusters, with more frequent dosing benefiting severe cases.

Comparing AI Models for Dermatological Diagnoses

Researchers emphasized the need for improved reliability and regulatory frameworks for AI tools before they are integrated into dermatological practice.

Delving Into NP/PA Perspectives on Emerging Atopic Dermatitis Treatment Options

Explore how surveyed providers perceive current and emerging therapies in the atopic dermatitis.

Study Solidifies Link Between Environment and Psoriasis Risk

Researchers linked higher exposure to natural environments and green spaces with an increased risk of developing psoriasis.