The Weekly Roundup: January 15-19

DermTech’s 2-GEP Assay Succeeds at Guiding Biopsy Decision-Making for Ambiguous Skin Lesions of All Skin Phototypes

The promising results were presented in a poster at the 2024 Winter Clinical Hawaii Dermatology Conference in Honolulu, Hawaii.

Roflumilast Foam, 0.3% Clears Seborrheic Dermatitis in Patients Who Reported Inadequate Response to Topical Steroids

Data from Arcutis’ STRATUM study was presented at the 2024 Winter Clinical Hawaii Dermatology Conference.

Majority of Patients Treated With Roflumilast Cream 0.15% for AD Demonstrate Improvement in EASI Scores at 4 Weeks

The pooled analyses from Arcutis’ INTEGUMENT-1 and INTEGUMENT-2 studies were presented at the 2024 Winter Clinical Hawaii Dermatology Conference.

COVID-19 Vaccination May Increase Risk of Pityriasis Rosea, Similar Eruptions

Additional studies are needed to adopt preventative measures and identify patients who may be deemed "at risk."

Harnessing the Potential of Placental Allografts

Placental tissues provide a promising alternative for addressing cutaneous reconstruction while maintaining the most cosmetically pleasing outcome.

Journal Digest: January 15

This week’s collection of the latest dermatologic studies covers the association between smoking and male pattern hair loss, immunohistochemical expression of angiotensin-converting enzyme-2 in the skin of patients with COVID-19, stiff skin syndrome, and pityriasis rosea and pityriasis rosea-like eruption following COVID-19 vaccination.

Review Indicates That Conventional GPP Therapies Are Still Widely Used, While Biologic Use is on the Rise in Japan

A recent retrospective cohort study described drug survival and treatment patterns among patients with newly-diagnosed generalized pustular psoriasis.

New Hyperhidrosis Treatment Approval Expected in Mid-2024 Following FDA Delay

The novel topical anticholinergic/antimuscarinic will offer an additional strategy for the treatment of underarm hyperhidrosis.

Procedures to Proceed and Avoid With Skin of Color

Seemal Desai, MD, highlighted the challenges and opportunities to best serve patients seeking solutions for acne scars, melasma, vitiligo, and cosmetic concerns.

Exploring Key Trends in Cosmeceuticals

Emmy Graber, MD, MBA, shared the truth behind cosmeceutical trends that patients may ask about from snail mucin to skin care refrigerators.

FDA Updates Dupilumab Label With Hand, Foot Atopic Dermatitis Involvement

The FDA has added efficacy and safety data for patients ages 12 years and older with uncontrolled moderate-to-severe atopic dermatitis with hand and/or foot involvement.

Dialing Into the Therapeutic Hotline with Gary Goldenberg, MD

The Winter Clinical Hawaii session delved into a spectrum of skin conditions, treatments, and common practice challenges.

Psoriasis Therapies in 2024 and Beyond

This article will highlight recently approved psoriasis therapies that will shape the 2024 treatment landscape and provide some exciting updates in the psoriasis management market this coming year and beyond.

New Imaging System Differentiates Between Melanoma and Nonmelanoma Nevi with 100% Sensitivity

A hand-held skin fluorescence imaging system shows promise in its ability to differentiate between concerning and non-concerning moles.

Review Explores Multifactorial Nature of Bone Health in Pediatric Patients With Epidermolysis Bullosa

Factors such as nutritional compromise, low levels of vitamin D, and more, negatively affect bone metabolism in this patient population.

Dermoscopy Combined With Reflectance Confocal Microscopy Improves Diagnostic Accuracy of AHLM/LMMs

A study found that combining dermoscopy with RCM not only improved diagnostic accuracy but also improved diagnostic certainty.

Changing Skin Microbiome, Signs of Aging Linked in New Study

The skin’s microbiome becomes more diverse with age, and this diversity correlates with crow’s feet lines, according to new research.

Clinical Trial Disparities, Alopecia Areata Misdiagnoses Prevalent Among Non-White Patients

Alopecia areata is more prevalent in non-White patients, according to findings of a recent study.

Social Media Dermatology Trends

In this month’s Cosmetic Conundrums article, Zoe Diana Draelos, MD, reviews 5 popular social media dermatology trends for dermatology clinicians to be aware of.

Microbial Analysis Reveals Potential Therapeutic Targets for Hypopigmentation in Lichen Striatus

The study suggests a relationship between an imbalance in the skin microbiota and LS-associated hypopigmentation.

Estrogen, Hormone Changes Play Role in Rosacea and Skin Alterations, Study Finds

The study explored the potential role of hormonal changes, specifically estrogen levels, in the pathogenesis of rosacea.

Which Patients With Psoriasis Will Develop Psoriatic Arthritis?

New evidence identifies factors that may predict which patients with psoriasis will develop psoriatic arthritis.

Vitamin D Shows Promise in Treating Skin Injured by Cancer Therapy

High-dose vitamin D helped improve radiation- and chemotherapy-induced skin injury in two patients undergoing cancer therapy.

Superficial X-Ray a Well-Tolerated, Non-Surgical Option for Basal and Squamous Cell Carcinomas

SXRT may present a cost-effective and surgery-free therapeutic option for patients with non-aggressive BCC and SCC.

RelabotulinumtoxinA Significantly Improved Glabellar and Lateral Canthal Lines in READY-3 Trial

This data builds upon data of the READY-1 and READY-2 trials, wherein relabotulinumtoxinA's duration of effect was validated.

Phase 1 Trial Underway for EVO756 in Adults With Chronic Spontaneous Urticaria

The study will evaluate the MRGPRX2 antagonist in healthy adults and adults with CSU.

Rare Immune Cell May Predict Immunotherapy Response in Melanoma

Vd1-gd T cells, a rare type of immune cell, have been found to potentially predict how likely it is that certain patients with advanced skin cancer will be responsive to treatment via immunotherapy, according to recently published research.

Pointers With Portela: Accutane vs Red Light Therapy for Acne

In this week’s Pointers With Portela, the 208SkinDoc compares Accutane to 5 Aminolevulinic acid with red light therapy.

FDA Clears DermaSensor Device for Skin Cancer Detection

The hand-held DermaSensor uses an AI algorithm to noninvasively evaluate suspicious skin lesions for cancer.

Skin Cancer Risk Not Increased Following Phototherapy Without Psoralens

A recent study explored the risk of skin cancer faced by patients undergoing phototherapy without psoralens.

POLL: Are You Attending the Maui Derm Hawaii 2024 Conference?

Click here to answer this week's conference poll.

Previewing Editorial Advisory Board Member Sessions at the Maui Derm Hawaii 2024 Conference

Among the many sessions to be held at the Maui Derm Hawaii 2024 conference on Maui, several Dermatology Times Editorial Advisory Board members are preparing to share their knowledge and insights.

Celltrion USA Launches 80 mg Dose of Adalimumab Biosimilar, Yuflyma

The high-concentration and citrate-free biosimilar was first available in a single 40 mg dose.

Cost-Saving 40-GEP Test in ART Decision-Making Reduces Over-Treatment

The 40-GEP test could help patients with skin cancer avoid adjuvant radiation therapy while simultaneously saving millions in health care costs.

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