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Botox impacts brain? Italian animal study raises safety concerns about botulinum toxin
June 1st 2008A recent animal study has shown that botulinum toxin injections can travel through retrograde axonal transport to unintended sites, including those in the brain, according to researchers at the Italian National Research Council's Istituto di Neuroscienze.
Opinion: SPF debate: FDA revamps sunscreen safety labeling
June 1st 2008The Food and Drug Administration has been revamping sunscreen safety labeling since the implementation of the final monograph was delayed in 2002. Last August, the FDA issued proposed guidelines for the product labels, with a comment period open until November, 2007. The deadline for comment was extended until late December, and as of May first no new guidelines had been announced.
New study verifies value of CSE - with or without dermoscopy
May 6th 2008Graz, Austria - Though complete skin examination (CSE) by dermoscopy takes longer to conduct than CSE alone when screening for skin cancer, physicians should consider three-minute screening for the disease with either method, according to the results of a study reported by MedScape Today.
Study links high IL-12 levels, increased melanoma mortality
May 6th 2008Houston - Data from a large cohort study shows that an elevated level of interleukin-12 is associated with a significantly increased mortality risk in patients with stage III melanoma with regional metastasis, according to MedPageToday.
Enbrel yields striking improvement in kids
May 1st 2008A phase 3 double-blind, placebo-controlled study shows remarkable efficacy of etanercept for treating pediatric psoriasis, bettering even those results observed in adults. The findings could help pave the way for Food and Drug Administration approval of the biologic, which could change the face of systemic treatment of psoriasis in children.
Psoriasis: New biologics coming closer to market
May 1st 2008Newer biologics to treat psoriasis are currently in late stages of development, and promising data from phase 2 and phase 3 clinical trials should give patients reason to hope. The biologics may be available as early as the end of 2008 or during 2009.
New actinic keratoses therapies take shape: Cosmetic component will always cloud reimbursement
May 1st 2008In the treatment of actinic keratoses, Peplin, a topical gel made from the sap of the Australian Euphorbia peplus, and cosmetic therapies show promise for preventing recurrences, but likely won't ever be front-line treatments. Meanwhile, the one treatment approved by the U.S. Food and Drug Administration treatment that also offers cosmetic benefits, ALA-PDT, comes with coding issues that some say make it difficult for doctors to obtain reasonable compensation.
Imiquimod has potential for treating Bowen's disease, possibly leishmaniasis
May 1st 2008New research indicates that topical imiquimod has potential for treating conditions ranging from Bowen's disease to leishmaniasis. Problems with inflammation and recurrences of conditions such as actinic keratosis, however, are still being investigated.
Antihistamine relieves atopic dermatitis itch
May 1st 2008Vapitadine (Barrier Therapeutics) is an investigational oral antihistamine that belongs to a new structural class of H1-selective, nonsedating agents. Results of a randomized, placebo-controlled clinical trial in adults with atopic dermatitis demonstrated its efficacy for relieving itch and added to an existing database showing vapitadine has an excellent safety profile.
Photodynamic therapy for nonmelanoma skin cancers: Nonsurgical route is safe, effective
May 1st 2008Photodynamic therapy is a safe, effective treatment for nonmelanoma skin cancers, according to an expert. Though the therapy is not yet approved for the treatment of skin cancer in the U.S., It has been accepted, approved, and recommended as a potential first-line of therapy for superficial basal cell carcinomas, and some superficial squamous cell carcinomas outside the U.S.
Healing open wounds: The 'right' topical insulin can expedite closure
May 1st 2008Researchers in the past have tried many different approaches to treating burn wounds and leg ulcers, including topical insulin, achieving mixed success. A recent study showed that the use of the right topical insulin could significantly speed up the wound healing process and wound closure.