- Acne
- Actinic Keratosis
- Aesthetics
- Alopecia
- Atopic Dermatitis
- Buy-and-Bill
- COVID-19
- Case-Based Roundtable
- Chronic Hand Eczema
- Drug Watch
- Eczema
- General Dermatology
- Hidradenitis Suppurativa
- Melasma
- NP and PA
- Pediatric Dermatology
- Pigmentary Disorders
- Practice Management
- Precision Medicine and Biologics
- Prurigo Nodularis
- Psoriasis
- Psoriatic Arthritis
- Rare Disease
- Rosacea
- Skin Cancer
- Vitiligo
- Wound Care
Advancing Care in Pediatric Plaque Psoriasis: Emerging Treatments and Management Strategies : Episode 8
Opinion
Video
Exploring the Role of MOA and PDE4 Pathways in Pediatric Patients with Plaque Psoriasis
Author(s):
Key Takeaways
- PDE4 inhibitors modulate inflammatory responses by increasing intracellular cAMP levels, reducing pro-inflammatory cytokine production.
- These agents offer a targeted approach, potentially minimizing side effects compared to traditional therapies.
Panelists discuss how phosphodiesterase-4 (PDE4) inhibitors, with their ability to modulate inflammatory pathways, hold promise as therapeutic targets for immune-mediated diseases like pediatric plaque psoriasis, offering unique benefits by potentially reducing inflammation with a favorable safety profile for pediatric patients.
Video Player is loading.
Video content above is prompted by the following:
- In light of the shifting treatment landscape, can you shed light on phosphodiesterase inhibitors-4 (PDE4), their nature, and why they hold promise as therapeutic targets for immune-mediated diseases like PP?
- How might its mechanism of action provide unique benefits for pediatric patients?
Related Videos
Utility of Molecular Testing in Skin Cancer Risk Assessment
Limitations and Challenges in Skin Cancer Staging Systems
Talking to Patients About the Safety of JAK Inhibitors in Atopic Dermatitis
Mechanism of Action Differences Among IL-17 Inhibitors
The Role of IL-17 in Psoriasis Pathogenesis
Navigating the Boxed Warning for the JAK Inhibitor Class
Personalized Photoprotection Based on Patient Factors
Impact of Oxidative Stress on Skin Health and the Utility of Antioxidants
Laboratory Monitoring for JAK Inhibitors and Key Takeaways
Options for Eyebrow and Eyelash Regrowth in a 32-Year-Old Female With Alopecia Areata
Related Content
