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Optimizing Management of Atopic Dermatitis and Alopecia Areata: From First-Line to Second-Line Treatments and Safety Protocols

Opinion
Video

Robert Bruce Posnick, MD, examines a case of a 55-year-old female patient with a 50-year history of atopic dermatitis, comorbid asthma, and severe alopecia areata, presenting with recurrent patches throughout her body, predominantly affecting her face, hands, trunk, arms, legs, and eyelids.

  1. What is your impression of this case? What challenges does this case present with, if any?
  2. What co-morbidities do you typically see with Atopic Dermatitis?
  3. Given her history, would you treat systemically? If so, oral JAK or injectable biologic?
  4. Would you consider a topical JAK, ie ruxolitinib? If so, any concern using topical JAK in combo with systemic therapy, if so which ones?
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