Roflumilast: Mechanism, and Use for Proactive AD Management
November 15th 2024Panelists discuss common misconceptions about the mechanism of action of PDE4 inhibitors in clinical practice, emphasizing that not all PDE4 inhibitors are created equal and how these differences can significantly impact their efficacy and safety profiles.
PDE4 Inhibitor Roflumilast for AD
November 15th 2024Panelists discuss the current landscape of topical treatments for atopic dermatitis, focusing on the evolution of nonsteroidal options over the past decade, and explain the mechanism of action of PDE4 inhibitors in specifically targeting inflammatory pathways associated with the condition.
Comparing the Efficacy of Roflumilast and Crisaborole
November 15th 2024Panelists discuss how topical PDE4 inhibitors compare to traditional treatments like corticosteroids in terms of efficacy, safety, and long-term disease control, while also examining the unique formulations of roflumilast and crisaborole and their implications for skin penetration and patient experience; they highlight practical considerations for application, the management of adverse effects such as stinging and burning, and the distinct advantages of PDE4 inhibitors in addressing specific gaps in atopic dermatitis management for various patient subgroups.
Evolution of Topical Treatment for AD
November 8th 2024Panelists discuss the current landscape of topical treatments for atopic dermatitis, focusing on the evolution of nonsteroidal options over the past decade, and explain the mechanism of action of PDE4 inhibitors in specifically targeting inflammatory pathways associated with the condition.
Insights on Topical Ruxolitinib: Rapid Itch Relief and Pediatric Considerations in Atopic Dermatitis
April 19th 2024Dermatology experts evaluate topical ruxolitinib cream's effectiveness in rapidly relieving itch and offer guidance on its black box warning. They also discuss its efficacy in children under 2, highlighting its suitability for those with tactile sensitivity.
Understanding Efficacy and Real-World Application of Topical Non-Steroidal Treatments for AD
April 19th 2024Dr James Del Rosso underscores the importance of phase 2 and dose-ranging studies to uncover efficacy differences between therapies, while the panel explores how clinical data from ruxolitinib trials mirrors real-world outcomes.
Clinical Perspectives: Addressing Unmet Needs in Topical Atopic Dermatitis Treatment
April 19th 2024James Del Rosso, DO, Brad Glick, DO, MPH, FAAD, and Lisa Swanson, MD, FAAD, address the demand for non-steroidal treatment alternatives while navigating the individualization of data interpretation regarding these treatments.
Looking Ahead: A Conversation Surrounding Closing the Gaps in Plaque Psoriasis Management
January 9th 2024Drs Lisa Swanson and Robert J. Casquejo express their optimism for the future of plaque psoriasis management, sharing their vision for expanded treatment approvals in the pediatric population affected by this condition.
Fostering Patient Wellness: Prioritizing Safety and Education in PDE4 Utilization
January 9th 2024Experts in dermatology highlight the crucial role of setting treatment response expectations and stress the need for discussions on managing mild plaque psoriasis, highlighting the utilization of systemic therapies in this context.
Exploring PDE4 Inhibitors in the Management of Plaque Psoriasis
January 4th 2024Lisa Swanson, MD, FAAD and Robert J. Casquejo, PA-C discuss the shifting treatment landscape, shedding light on phosphodiesterase inhibitors-4 (PDE4) and comment on why it holds promise as a therapeutic target for immune-mediated diseases.
Understanding Plaque Psoriasis: Navigating Impact on Patients with Moderate and Mild Disease
December 19th 2023Lisa Swanson, MD, FAAD and Robert J. Casquejo, PA-C highlight the impact of plaque psoriasis on both moderate and mild patients, emphasizing the importance of addressing these concerns in patient care.