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Journal Digest: April 8
This week’s collection of the latest dermatologic studies covers circulating tumor DNA in advanced cSCC, targeting IL-13 with tralokinumab in AD, a pediatric lymphoplasmocytic plaque case report, and skin of color reporting in randomized controlled trials focusing on SCC.
Springing Into the Latest Research in Dermatology
In an introduction to our April publication, explore an overview of topics covered in this issue and an introduction to our Spring Editor in Chief, Aaron Farberg, MD.
Phase 1b Data for Topical Pravibismane in Diabetic Foot Ulcer Infection Demonstrates Favorable Effects and Safety
Data was recently published in the International Wound Journal supporting positive outcomes in moderate or severe ulcers.
The Cutaneous Connection: Make Data-Driven Decisions For Personalized AD Treatment
Christopher Bunick, MD, PhD, delves into current data and guidelines to consider when creating custom treatment plans for patients with atopic dermatitis.
QUIZ: Test Your Knowledge of Rosacea Etiology, Types, and Triggers
Click here to read more and answer our quiz questions in recognition of Rosacea Awareness Month.
Derm In The News: March 31-April 6
Keep up with the latest headlines in dermatology from the past week, including the launch of an expanded job board for dermatology support roles, CMS and Incyte's collaboration for povorcitinib in China and Southeast Asia, and more.
The Weekly Roundup: April 1-5
ICYMI, this week we had news about Ycanth's J-code launch, highlights from Diversity in Dermatology, bimekizumab's accepted sBLA for HS, and more.
Increased Levels of B-Type Natriuretic Peptide May be Associated With Various Types of Chronic Itch
Gil Yosipovitch, MD, discusses the correlation between increased BNP levels and chronic pruritus of unknown origin.
Countdown to RAVE!
Three distinct congresses known as RAVE (Revolutionizing Atopic Dermatitis, Alopecia Areata, and Vitiligo) will be held June 8-10, in Chicago, Illinois.
Topical Permethrin Demonstrates Lack of Efficacy Compared to Benzyl Benzoate in Most Scabies Cases
In a comparative study, benzyl benzoate demonstrated superior efficacy in scabies cases, while topical permethrin exhibited a lack of effectiveness.
Omalizumab for Chronic Spontaneous Urticaria Does Not Yield Negative Maternal, Fetal Outcomes in Pregnancy
Researchers reviewed the efficacy and safety of omalizumab in patients with severe CSU in a routine clinical practice setting.
Managing Mental Health Comorbidities in Adult Patients With Atopic Dermatitis
Researchers address the persisting gaps in managing mental health comorbidities within the framework of existing clinical practice guidelines.
Be Proactive When Combatting Tanning Bed Misinformation on Social Media
Influencers promote the use of tanning beds and list the “benefits,” such as obtaining vitamin D and helping with seasonal affective disorder, among other reasons that have no merit.
Journal Digest: April 4
This week’s collection of the latest dermatologic studies covers topical permethrin 5% vs. benzyl benzoate 25% for scabies, the safety of omalizumab in CSU during pregnancy, symptoms of cognitive impairment in children with AD, and the ethics of cosmetic overtreatment.
Botulinum Toxin, Dermal Fillers Generally Effective and Well-Tolerated in Skin of Color Populations
In a literature review, researchers found data supporting the efficacy and safety of fillers in patients with skin of color, particularly for populations where is there is limited data.
Topical Melatonin and Rosuvastatin Reduce Severity of Mild to Moderate Plaque Psoriasis
Versus placebo, topical melatonin and rosuvastatin reduced psoriatic plaque severity with a favorable safety profile.
FDA Accepts Supplemental Biologics License Applications for Bimekizumab to Treat HS
The submission stems from promising results from the phase 3 BE HEARD I and BE HEARD II trials.
Dupilumab Shows Superiority in Reducing Upper Respiratory Infections in Patients With AD
The risk of upper respiratory infection-related mortality was notably diminished in the study's dupilumab cohort.
Elevated Plasma Calcitonin Gene-Related Peptide Levels in Patients With Rosacea May Open Door for New Therapeutic Approaches
One study uncovered high levels of CGRP in patients with rosacea, with levels not affected by age, sex, BMI, and other factors.
New Data on Retinol: Patricia Farris, MD, Shares Insights on Anti-Aging
In this study, topical 0.1% retinol significantly improved crow’s feet, facial wrinkles, uneven skin tone, brown spots, and overall photoaging.
Pointers With Portela: Effects of Hormone Changes on the Skin
In this week’s Pointers With Portela, the 208SkinDoc reviews how the skin is affected during hormonal changes and menopause.
Pelthos Therapeutics Launches to Accelerate Commercialization of Treatment for Molluscum Contagiosum
The new launch is set to bring berdazimer topical gel, 10.3% to adults and pediatric patients over the age of 1 with molluscum contagiosum faster.
ARCA Biopharma and Oruka Therapeutics Agree to Merger
The merger will focus on advancing Oruka’s portfolio of novel biologics for the treatment of chronic skin diseases.
Soligenix and European Medicines Agency Settle on Design of Second Placebo-Controlled Trial of HyBryte in CTCL
The agreement for a second confirmatory trial comes after a successful phase 3 FLASH study that yielded positive outcomes and efficacy.
Microneedling With and Without N-acetylcysteine Prove Effective in Patients With Persistent Vitiligo
While the addition of NAC yielded greater improvement than microneedling alone, this difference was not significant.
Muneeb Shah, DO: Behind the Scenes of Launching a Skin Care Brand
Shah discusses the science behind his products, as well as the challenges he didn’t anticipate when launching Remedy.
Recapping March Dermatology Biosimilar News
The biosimilar landscape experienced significant activity, marked by fresh data from conferences, novel findings regarding adalimumab biosimilars, and more.
Mona Shahriari, MD, FAAD: 'The Days of Paternalistic Medicine Are Gone'
Shahriari shares pearls and considerations from her sessions at the recent Diversity in Dermatology conference.
Patients With Vitiligo Show Lower Pulmonary Embolism and Peripheral Vascular Disease Risk, but Mortality Rises with Comorbidities
A recent study aimed to investigate the risk of myocardial infarction, cerebrovascular accident, peripheral vascular disease, and pulmonary embolism in patients with vitiligo.
Mastering the Challenges of Adult Female Acne in Primary Care in 2024
Over 50% of women in their 20s and over 35% of women aged 30 to 39 years struggle with adult female cystic acne.